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- The nurse is preparing to give Acetaminophen to a 5year old girl weighing 20 kg. The doctor has ordered Acetaminophen 240mg PO qehr PRN pain. the safe dose range for acetaminophen is 10-15 MG/KG/dose. What is the low safe amount per dose? [1] What is the high safe amount per dose? (2) is this dose safe to give? (3]1.) The recommended initial once-a-day dose of the neurologic drug divalproex sodium is 25 mg/kg/day, to be increased as indicated to an absolute maximum dose of 60 mg/kg/day. Calculate these quantities for a 182-lb patient. 2.) Diproex sodium is available in 250 mg and 500 mg strength tablets. From the information in the previous problem, what strength tablet and quantity could a pharmacist recommend for an initial dose?3) An IV Piggyback of lincomycin containing 5 gms of drug in 175 mL is to be infused over a 1 hour period. The IV set is calibrated to deliver 12 gtt/mL. How many drops per minute should be administered?
- Mrs B, aged 43 years, weight 56 kg, requires a loading dose of drug B. The target plasma concentration is 18.9 mg/ L, volume of distribution is 0.5 L/ kg, the salt factor is 0.9 and bioavailability fraction is 1. What is the intravenous loading dose (LD) of Drug B in milligrams (mg)? units - mg LD = Cp desired x Vd S x F Where Cp desired is the target plasma concentration; Vd is the volume of distribution; S is the salt factor and F is the bioavailability fractionDaisy (7 years old; 30 kg) is admitted to hospital for meningitis and requires a short intravenous infusions of cefotaxime. A dose of 50 mg/kg is recommended every 6 hours for the first 4 days. Only 2 g cefotaxime vials are available. The powder in the vials is dissolved with 4.0 mL of saline. Calculate the volume (in mL to 1 d.p.)of this solution which should be transfered to the 40mL syringe driver for a single infusion.17. What is the infusion rate in mL/min for the prescription below? Sodium Nitrite (30 mg/mL) 8 ml Normal Saline qs ad 500 mL Sig: Infuse 140 mcg/kg/hr for a patient who weighs 175 lbs 18. If the dropper delivers 2 mL in 55 drops, how many drops of peppermint oil should be used if the Rx calls for 0.6 mL? [Round to closest whole number] 19. A hospital pharmacist fills a medication order for 80 mEq of magnesium sulfate, Mg(SO4), in a total volume of 2 L of 0.9% sodium chloride injection. If 560 mL of the infusion have been administered so far, how many mEq of MgSO4 have been administered? [Report to 1 decimal place] 20. If 1 L of magnesium sulfate solution is administered over 12 hours using an administration set that delivers 20 gtts/mL, what is the infusion rate in gtts/min?
- 1. How many ml of propofol (10 mg/ml) is necessary to induce a patient weighing 30 kg for surgery at a dose of 6 mg/kg? 2.How many mL of Midazolam (5mg/ml) should be given to a patient weighing 3.6 kg at a dose of 0.3mg/kg? 3.6) Calculate these medications for a 12.5 pound dog.-Carprofen (Rimadyl) = 4.4mg/kg (50mg/ml bottle)- Meloxicam (Metacam) = 0.2 mg/kg (1.5 mg/ml bottle)- Robenacoxib (Onsior) = 2mg/kg (bottle 20mg/ml)- Diphenhydramine (Benadryl) = 1.5 mg/kg (125 mg/5 ml bottle)3) A child is prescribed 15/kg/day of paracetamol in 4 divided doses. Child weight 16kg, stock strength available is 120mg in ml liquid. What would be the volume of medication given in single dose ?
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