1.1 Propose the reaction mechanism for the formation of the products formed in eachof the reactions in the scheme below. Clearly show the stereochemistry of A and Band explain their formation.ⒸPPh₂PPh3.CHONaHn-BuLiCOMeMeO₂CACHO1.2 The reagent, (MeO)2P=O(CH₂CO₂Me), is treated with sodium methoxide and theresultant species is then reacted with the following compound:CHOGive the product(s) of each step the reaction sequence.B

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1.1 Propose the reaction mechanism for the formation of the products formed in each of the reactions in the scheme below. Clearly show the stereochemistry of A and B and explain their formation. Ⓒ PPH3 @ PPH3 CHO NaH n-BuLi COMe MeO₂C A CHO 1.2 The reagent, (MeO)2P=O(CH₂CO2Me), is treated with sodium methoxide and the resultant species is then reacted with the following compound: CHO Give the product(s) of each step the reaction sequence. B

1.1 Propose the reaction mechanism for the formation of the products formed in each of the reactions in the scheme below. Clearly show the stereochemistry of A and B and explain their formation. Ⓒ PPH3 @ PPH3 CHO NaH n-BuLi COMe MeO₂C A CHO 1.2 The reagent, (MeO)2P=O(CH₂CO2Me), is treated with sodium methoxide and the resultant species is then reacted with the following compound: CHO Give the product(s) of each step the reaction sequence. B

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter18: Functional Derivatives Of Carboxylic Acids

Section: Chapter Questions

Problem 18.38P: A step in a synthesis of PGE1 (prostaglandin E1, alprostadil) is the reaction of a trisubstituted...

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