A poison that prevents the transfer of electrons from the last [Fe-S] cluster of Complex I to coenzyme Q is added to a suspension of actively respiring mitochondria. Which of the following will be observed? ATP production would be impaired due to the uncoupling of oxidative phosphorylation from electron transport. ATP production would be reduced due to inhibition of the CoQ subunit of ATP synthase. ATP production would be reduced due to a decrease in the number of protons pumped out of the mitochondrial matrix. ATP production would be halted completely due to the block in electron transport through the electron transport chain.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter2: Cell Physiology
Section: Chapter Questions
Problem 10RE: Using the answer code on the right, indicate which form of energy production is being described: 1....
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A poison that prevents the transfer of electrons from the last [Fe-S]
cluster of Complex I to coenzyme Q is added to a suspension of
actively respiring mitochondria. Which of the following will be
observed?
ATP production would be impaired due to the uncoupling of
oxidative phosphorylation from electron transport.
ATP production would be reduced due to inhibition of the CoQ
subunit of ATP synthase.
ATP production would be reduced due to a decrease in the
number of protons pumped out of the mitochondrial matrix.
ATP production would be halted completely due to the block in
electron transport through the electron transport chain.
Transcribed Image Text:A poison that prevents the transfer of electrons from the last [Fe-S] cluster of Complex I to coenzyme Q is added to a suspension of actively respiring mitochondria. Which of the following will be observed? ATP production would be impaired due to the uncoupling of oxidative phosphorylation from electron transport. ATP production would be reduced due to inhibition of the CoQ subunit of ATP synthase. ATP production would be reduced due to a decrease in the number of protons pumped out of the mitochondrial matrix. ATP production would be halted completely due to the block in electron transport through the electron transport chain.
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