Agamemnon just got his first octapeptide to sequence. Identify the correct sequence from the data gathered below. He first did a complete acid hydrolysis and identified the amino acids using HPLC. He found he had a lle, Ala, Ser, Asp, Asn, Phe, His, and an Arg. He submitted the octapeptide to conditions of Edman degradation and got the structure below. S. HO He used carboxypeptidase and generated a His and a heptapeptide. He used chymotrypsin and generated a 5-amino acid sequence and a 3-amino acid sequence. He used trypsin and generated a 2-amino acid sequence and a 6-amino acid sequence. Partial hydrolysis of the nonapeptide yielded the fragments RIS, NAH, and SF among others.

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins
Section26.1: Structures Of Amino Acids
Problem 1P: How many of the -amino acids shown in Table 26-1 contain aromatic rings? How many contain sulfur?...
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Agamemnon just got his first octapeptide to sequence. Identify the correct sequence from the data gathered
below.
He first did a complete acid hydrolysis and identified the amino acids using HPLC. He found he had a lle, Ala, Ser, Asp,
Asn, Phe, His, and an Arg.
He submitted the octapeptide to conditions of Edman degradation and got the structure below.
H.
но
He used carboxypeptidase and generated a His and a heptapeptide.
He used chymotrypsin and generated a5-amino acid sequence and a 3-amino acid sequence.
He used trypsin and generated a 2-amino acid sequence and a 6-amino acid sequence.
Partial hydrolysis of the nonapeptide yielded the fragments RIS, NAH, and SF among others.
Transcribed Image Text:Agamemnon just got his first octapeptide to sequence. Identify the correct sequence from the data gathered below. He first did a complete acid hydrolysis and identified the amino acids using HPLC. He found he had a lle, Ala, Ser, Asp, Asn, Phe, His, and an Arg. He submitted the octapeptide to conditions of Edman degradation and got the structure below. H. но He used carboxypeptidase and generated a His and a heptapeptide. He used chymotrypsin and generated a5-amino acid sequence and a 3-amino acid sequence. He used trypsin and generated a 2-amino acid sequence and a 6-amino acid sequence. Partial hydrolysis of the nonapeptide yielded the fragments RIS, NAH, and SF among others.
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