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- 9. Which of the following molecules is the least water soluble? НО. ОН Н НО `NH2 dopamine Н a. НО estradiol c. НО -NH НО ОН b. adrenalin Н HO d. cholesterol1. An inactive or much less active form of drug which transformed to active drug in the body is a. Coated drug b. Specialized dosage form c. Prodrug d. Reservoir 2. Sodium pump is an example of a. G-protein receptors b. Ion channels c. Gene Transcription linked receptor d. Enzyme-linked tyrosine kinase3. As the length of a non-polar chain of aliphatic alcohol increases, its solubility in water a. Increases b. Decreases c. No effect 4. More common force of attraction for drugs a. Covalent b. Electrostatic c. Hydrogen bonding d. Ionic5. In organs and tissues that are well-perfuse, drug distribution is a. Faster b. Slower c. Negligible d. The sameThe newer anxiolytic drug that shows little risk for dependence in animal studies is called: O Ambien. O Rohypnol. O Mescaline. O BuSpar.
- Nonsteroidal anti-inflammatory drugs, often referred to as NSAIDS, are commonly used to treat minor aches and pains. Four of the most common NSAIDS are: CH3 H нн H H. H3C. OH CH3 HO. H H CH3 Acetylsalicylic acid (aspirin) Ibuprofen (Advil, Nuprin, Motrin) H H. H H. ОН H3C Н. H. HO. H. H H CH3 H H3C Naproxen (Naprosyn, Aleve) Acetaminophen (Tylenol) (a) How many sp3-hybridized carbons are present in aspirin? (b) How many sp2-hybridized carbons are present in naproxen? (c) What is the molecular formula of acetaminophen? (d) Aspirin, ibuprofen, and naproxen are all believed to target the same enzyme, cyclooxygenase, which produces substances called prostaglandins, that mediate inflammation. Discuss in the structures of these drugs. any similarities17. Is caffeine an addictive substance? If so, is it psychologically addictive, physiologically addictive, or both? What about chocolate? Bubble gum? How are such distinctions made? A common scene in movies and TV programs shows the detective tasting a suspected drug powder to determine its identity. In addition to being poor laboratory practice, it is a really bad idea. Discuss and explain. 18.1. The Ability of a substance to exist in different crystalline form a. Lattice b. Polymorphism c. Crystallization d. Amphoterism 2. A drug can exert its pharmacological effect only if it is a. Protein bound b. Protein unbound c. Free drug d. Both B & C e. Both A & C 3. In order for the drug to be ready and available for absorption, it must be release first from its dosage form with the exception of: a. Capsule b. Tablet c. Solution d. Suspension 4. All of the following are true, except a. Solubility increase with decrease particle size b. Solubility increase with increase surface area c. Solubility increase with increase particle size d. Solubility decrease with decrease surface area 5. The rate in which the drug appears in the bloodstream is also known as a. Half-life b. Potency c. Bioavailability d. Area under the curve
- Uber Eats Problem 31 of 32 mCPBA CH2Cl2 Select to Draw 1. NaCN 2. H₂O 8 Min Submit1. CH3CO3H 2. H₂O* ?I. Enzymes are globular proteins II. Enzymes react with specific substrate. III. Enzymes are biodegradable substances. O All statements are correct O All statements are wrong O Statements I & II are correct. O Statements I & III are correct O Statemnets II & III are correct Dietary proteins yield amino acids and are deposited in the nitrogen pool. O True O False