If a particular 150 amino acid polypeptide is known to sample 4 preferred states as it folds into its native protein conformation, and if 10¹5 conformations can be sampled per second, then how many hours would it take for this protein to fold according to Leventhal?

If a particular 150 amino acid polypeptide is known to sample 4 preferred states as it folds into its native protein conformation, and if 10¹5 conformations can be sampled per second, then how many hours would it take for this protein to fold according to Leventhal?

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter22: Proteins

Section: Chapter Questions

Problem 22.62P: 22-62 Distinguish between intermolecular and intramolecular hydrogen bonding between backbone...

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1. Calculate the Coulombic (ionic) interaction energy between atoms for the C=O ∙∙∙H-N hydrogen bond in a peptide at a distance of 1.5Å in units of kJ/mol. Assume that the partial charge on O is −0.434, the partial charge on H is +0.417 and the permittivity of the protein environment is 6. coulimbic interaction energy= 27.95 kJ/mol 2. The dipole moment of an individual peptide group is approximately 3.46 D. Assuming that the dipoles line up linearly estimate the energy of interaction (in kJ.mol) of the hydrogen bond in Q1 using a dipole-dipole model. *******please answer #2**********
Calculate the (a) Linearity constant (r), (b) y-intercept, (c) Slope, and (d) Protein content of an unknown sample having an absorbance of 0.325.
a. Calculate the Coulombic (ionic) interaction energy between atoms for the C=O ∙∙∙H-N hydrogen bond in a peptide at a distance of 1.5Å in units of kJ/mol. Assume that the partial charge on O is −0.434, the partial charge on H is +0.417 and the permittivity(Er) of the protein environment is 6. b. The dipole moment of an individual peptide group is approximately 3.46 D. Assuming that the dipoles line up linearly estimate the energy of interaction (in kJ.mol) of the hydrogen bond in Q1 using a dipole-dipole model. please help me! this is for an upper division physical chemistry course, so showing work would be appreciated
22-49 Based on your knowledge of the chemical properties of amino acid side chains, suggest a substitution for leucine in the primary structure of a protein that would probably not change the character of the protein very much.
22-62 Distinguish between intermolecular and intramolecular hydrogen bonding between backbone groups. Where in protein structures do you find one, and where do you find the other?
There is a class of polyesters that have the general structure shown below. For example, in polyethylene terephthalate (PET) m =1. How would you expect the Tg ad Tm of these polymers to vary with m, given that the molecular weight of the chain is held constant? Give reasons for your answer. Also, assuming that you are now just considering one member of this class of polymers, say PET, how does the Tg vary with molecular weight, n.
Assume a pH gradient of 4.0 units across a thylakoid membrane, with the lumen more acidic than the stroma.The intensity of natural sunlight drops off dramatically beyond 650 nm.Calculate the maximum number of moles of protons that could be pumped against the gradient by the energy in a mole of photons of 650 nm wavelength. Assume 100% efficiency and T = 25 °C for this calculation.
A ALEKS - Julianna Graham - L x + ← → www-awu.aleks.com/alekscgi/x/Isl.exe/10_u-IgNslkr7j8P3JH-IQUHIQg6bJxmeSyVPHOEB1plef9xyC5Ca9QIUX9FDNS1kHQvOMzcrVprA IBP5q2HYWPCASZQKNla...✰ Ο Naming and Drawing Organic Molecules Numbering the main chain of branched alkanes For each organic compound in the table below, enter the locant of the highlighted side chain. compound locant of highlighted side chain CH₂ CH3-CH2-C- CH₂ T CH3 CH₁₂ | CH3-CH2-CH-CH-CH3 CH3 CH3 CH3-CH2-CH- CH3 Explanation Check esc F2 DOD D MacBook Air # 80 $ 000 F4 % & G F7 0/5 Julianna olo 2024 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center Accessibility FB F10 dele
A ALEKS - Julianna Graham - L x + → www-awu.aleks.com/alekscgi/x/Isl.exe/10_u-IgNslkr7j8P3jH-IQUHIQg6bJxmeSyVPHOEB1plef9xyC5Ca9QlcCnFtj2g_ocV9yqjhTA6txxlkZNocVVr1afz5U7yLfdH9E... Naming and Drawing Organic Molecules Comparing skeletal structures related by one fewer bond Could we cut just one bond in the "starting" molecule shown in the drawing area below to create this "target" molecule? The target molecule. If so, highlight the bond to be cut. If not, check the box under the drawing area that says Not possible. Note: it's OK if cutting the bond creates more than one molecule, as long as one of them is the target molecule. 3/5 Julianna × 5 c Ar Not possible. Note for advanced students: what we mean by "cutting" the bond here is breaking the bond and attaching H atoms to each dangling end, like this: Explanation Check MacBook Air 2024 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center Accessibility
D.D. Nelson et al. (Science 238, 1670 (1987)) examined several weakly bound gas-phase complexes of ammonia in search of examples in which the H atoms in NH3 formed hydrogen bonds, but found none. For example, they found that the complex of NH3 and CO2 has the carbon atom nearest the nitrogen (299 pm away): the CO2 molecule is at right angles to the C–N ‘bond’, and the H atoms of NH3 are pointing away from the CO2. The magnitude of the permanent dipole moment of this complex is reported as 1.77 D. If the N and C atoms are the centres of the negative and positive charge distributions, respectively, what is the magnitude of those partial charges (as multiples of e)?
11) Using the data: C₂H4(8), AH°f=+51.9 kJ mol-1, S = 219.8 J mol-1 K-1 CO₂(g), AH°f = -394 kJ mol-¹, So=213.6 J mol-1 K-1 H₂O(1), AH°f = -286.0 kJ mol-¹, S = 69.96 J mol-¹ K-1 O₂(g), AH°f = 0.00 kJ mol-¹, So = 205 J mol-1 K-1 Calculate the maximum amount of work that can be obtained, at 25.0 °C, from the process: C₂H4(g) + 3 O₂(g) → 2 CO₂(g) + 2 H₂O(l) A) 1492 kJ mol-1 B) 1380 kJ mol-1 C) 1451 kJ mol-1 D) 2422 kJ mol-1 E) 1332 kJ mol-1 252253010 armitoron (simodo estoitumoleriam nosalmatinon (d
Explain the differences between molecular conjugation and bioconjugation for advanced drugdelivery. Please provide an example of each