Threatened species often have small, isolated populations where mating between relatives occurs. Let's assume one of these threatened species has a disease controlled by a gene that has two alleles A and a. Only individuals with two copies of the "a" allele have the disease and die before reproducing.  Question:  What are the effects of inbreeding on the frequency of the "a" allele, and the frequency of the disease in the population?

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter19: Population Genetics And Human Evolution
Section: Chapter Questions
Problem 8QP: How Can We Measure Allele Frequencies in Populations? In a population where the females have the...
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Threatened species often have small, isolated populations where mating between relatives occurs. Let's assume one of these threatened species has a disease controlled by a gene that has two alleles A and a. Only individuals with two copies of the "a" allele have the disease and die before reproducing. 

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What are the effects of inbreeding on the frequency of the "a" allele, and the frequency of the disease in the population?

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