V Figure 7.9 Synthesis of membrane components and their orientation in the membrane. The oytoplasmic (orange) face of the plasma membrane differs from the extracellular (aqua) face. The latter arises from the irside face of ER, Golgi, and veside membranes. OMembrane protelns and lipids are synthesized in assoclation with the endoplasmic reticulum (ER). In the ER, carbohydrates (green) are added to the transmembrane proteins (purple dumbbells), making them glycoprotelns. lihe carbohydrate portions may then be modified. Lipid bilayer Secretory protein Golgi apparatus O Inside the Golgl apparatus, the glycoprotelns undergo further carbohydrate modification, and lipids | acquire carbohydrates, becoming glycoliplds. Transmembrane glycoproteins O The glycoprotelns, glycollipids, and secretory protelns (purple spheres) are transported in vesidles to the plasma membrane. Vesicle Attached carbohydrate OAs vesidles fuse with the plasma membrane, the outside face of the vesidle becomes continuous with the Inside (cytoplasmic) face of the plasma membrane. This releases the secretory protelns from the cell, a process called exocytosk, and positions the carbohydrates of membrane glycoprotelns and glycolipids on the outside |(extracellular) face of the plasma membrane. ER Glycolipid. ER lumen DRAW IT> Drawan integral membrane protain axtenaing from partway through the ER membrana into the ER lumen. Naxt, draw the protein where it would be located in a series of numbered staps ending at the plazma membrane. Would the protein contact the gytoplasm or the extracelular fluid? Explain Plasma membrane: cytoplasmic face. Transmembrane glycoprotein Secreted protein Extracellular face, Membrane glycolipid CHAPTER 7 Membrane Structure and Function 131

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Carbohydrates are attached to plasma membrane proteins in the ER (see Figure 7.9). On which side of the vesicle membrane are the carbohydrates during transport to the cell surface?

V Figure 7.9 Synthesis of membrane components and their orientation in the
membrane. The oytoplasmic (orange) face of the plasma membrane differs from the extracellular
(aqua) face. The latter arises from the irside face of ER, Golgi, and veside membranes.
OMembrane protelns and lipids are synthesized in
assoclation with the endoplasmic reticulum (ER). In the ER,
carbohydrates (green) are added to the transmembrane
proteins (purple dumbbells), making them glycoprotelns.
lihe carbohydrate portions may then be modified.
Lipid
bilayer
Secretory
protein
Golgi
apparatus
O Inside the Golgl apparatus, the glycoprotelns
undergo further carbohydrate modification, and lipids
| acquire carbohydrates, becoming glycoliplds.
Transmembrane
glycoproteins
O The glycoprotelns, glycollipids, and secretory
protelns (purple spheres) are transported in
vesidles to the plasma membrane.
Vesicle
Attached
carbohydrate
OAs vesidles fuse with the plasma membrane,
the outside face of the vesidle becomes
continuous with the Inside (cytoplasmic) face of
the plasma membrane. This releases the secretory
protelns from the cell, a process called exocytosk,
and positions the carbohydrates of membrane
glycoprotelns and glycolipids on the outside
|(extracellular) face of the plasma membrane.
ER
Glycolipid.
ER
lumen
DRAW IT> Drawan integral membrane protain
axtenaing from partway through the ER membrana into
the ER lumen. Naxt, draw the protein where it would
be located in a series of numbered staps ending at
the plazma membrane. Would the protein contact the
gytoplasm or the extracelular fluid? Explain
Plasma membrane:
cytoplasmic face.
Transmembrane
glycoprotein
Secreted
protein
Extracellular face,
Membrane
glycolipid
CHAPTER 7 Membrane Structure and Function
131
Transcribed Image Text:V Figure 7.9 Synthesis of membrane components and their orientation in the membrane. The oytoplasmic (orange) face of the plasma membrane differs from the extracellular (aqua) face. The latter arises from the irside face of ER, Golgi, and veside membranes. OMembrane protelns and lipids are synthesized in assoclation with the endoplasmic reticulum (ER). In the ER, carbohydrates (green) are added to the transmembrane proteins (purple dumbbells), making them glycoprotelns. lihe carbohydrate portions may then be modified. Lipid bilayer Secretory protein Golgi apparatus O Inside the Golgl apparatus, the glycoprotelns undergo further carbohydrate modification, and lipids | acquire carbohydrates, becoming glycoliplds. Transmembrane glycoproteins O The glycoprotelns, glycollipids, and secretory protelns (purple spheres) are transported in vesidles to the plasma membrane. Vesicle Attached carbohydrate OAs vesidles fuse with the plasma membrane, the outside face of the vesidle becomes continuous with the Inside (cytoplasmic) face of the plasma membrane. This releases the secretory protelns from the cell, a process called exocytosk, and positions the carbohydrates of membrane glycoprotelns and glycolipids on the outside |(extracellular) face of the plasma membrane. ER Glycolipid. ER lumen DRAW IT> Drawan integral membrane protain axtenaing from partway through the ER membrana into the ER lumen. Naxt, draw the protein where it would be located in a series of numbered staps ending at the plazma membrane. Would the protein contact the gytoplasm or the extracelular fluid? Explain Plasma membrane: cytoplasmic face. Transmembrane glycoprotein Secreted protein Extracellular face, Membrane glycolipid CHAPTER 7 Membrane Structure and Function 131
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