You are examining the effects of a mutation in the proximal histidine of a heme-containing protein. This mutation has changed the histidine into an alanine. Based on your knowledge of the role of heme in hemoglobin and how it is coordinated in the protein, what is the MOST likely effect of the mutation? Group of answer choices The heme will bind to O2 more effectively than to CO Heme will no longer be bound in the protein The iron in heme will be fully coordinated The iron in heme will have two uncoordinated bonds There will be no effect on heme binding due to this mutation
You are examining the effects of a mutation in the proximal histidine of a heme-containing protein. This mutation has changed the histidine into an alanine. Based on your knowledge of the role of heme in hemoglobin and how it is coordinated in the protein, what is the MOST likely effect of the mutation? Group of answer choices The heme will bind to O2 more effectively than to CO Heme will no longer be bound in the protein The iron in heme will be fully coordinated The iron in heme will have two uncoordinated bonds There will be no effect on heme binding due to this mutation
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter10: From Proteins To Phenotypes
Section: Chapter Questions
Problem 19QP: A person was found to have very low levels of functional beta globin mRNA and therefore very low...
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You are examining the effects of a mutation in the proximal histidine of a heme-containing protein. This mutation has changed the histidine into an alanine. Based on your knowledge of the role of heme in hemoglobin and how it is coordinated in the protein, what is the MOST likely effect of the mutation?
Group of answer choices
The heme will bind to O2 more effectively than to CO
Heme will no longer be bound in the protein
The iron in heme will be fully coordinated
The iron in heme will have two uncoordinated bonds
There will be no effect on heme binding due to this mutation
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