Concerning the reciprocal regulation of phosphofructokinase and fructose-1,6-bisphosphatase in the liver, which of the following statements are true? Select all that apply A.The default activity of the cell favors activity of phosphofructokinase-2 being activated, generating fructose-2,6-bisphosphate that serves as a potent allosteric activator of phosphofructokinase B.Glucagon binding ensures that the levels of fructose-2,6-bisphosphate drop within the liver cell C.In the presence of ATP and fructose-2,6-bisphosphate, phosphofructokinase will be fully inhibited and glycolysis turned off D.High levels of fructose-2,6-bisphosphate signals for activation of gluconeogenesis and inhibition of glycolysis E.Glucagon binding to the liver cell activates a phosphorylation cascade that inhibits activity of phosphofructokinase-2 and activates fructose-2,6-bisphosphatase F.Glucagon binding activates glycolysis as it signals high blood sugar levels

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
icon
Concept explainers
Question

Concerning the reciprocal regulation of phosphofructokinase and fructose-1,6-bisphosphatase in the liver, which of the following statements are true? Select all that apply

A.The default activity of the cell favors activity of phosphofructokinase-2 being activated, generating fructose-2,6-bisphosphate that serves as a potent allosteric activator of phosphofructokinase
B.Glucagon binding ensures that the levels of fructose-2,6-bisphosphate drop within the liver cell
C.In the presence of ATP and fructose-2,6-bisphosphate, phosphofructokinase will be fully inhibited and glycolysis turned off
D.High levels of fructose-2,6-bisphosphate signals for activation of gluconeogenesis and inhibition of glycolysis
E.Glucagon binding to the liver cell activates a phosphorylation cascade that inhibits activity of phosphofructokinase-2 and activates fructose-2,6-bisphosphatase
F.Glucagon binding activates glycolysis as it signals high blood sugar levels
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Metabolic pathways
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education