Draw the structure of the protected amino acid that must be anchored to the solid support in order to use a Merrifield synthesis to prepare leucine enkephalin. Include stereochemistry in your answer. Do NOT explicitly draw any hydrogen atoms in your structure or use abbreviations like OME, COOH or Ph. (N terminus) Try-Gly-Gly-Phe-Leu (C terminus)

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter26: Biomolecules: Amino Acids, Peptides, And Proteins
Section26.1: Structures Of Amino Acids
Problem 1P: How many of the -amino acids shown in Table 26-1 contain aromatic rings? How many contain sulfur?...
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Draw the structure of the protected amino acid that must be anchored to the solid support in order to use a Merrifield synthesis to
prepare leucine enkephalin. Include stereochemistry in your answer. Do NOT explicitly draw any hydrogen atoms in your structure or
use abbreviations like OMe, COOH or Ph.
(N terminus) Try-Gly-Gly-Phe-Leu (C terminus)
НО.
H₂N
✔ Edit Drawing
H₂C
CH₂
OH
Transcribed Image Text:Draw the structure of the protected amino acid that must be anchored to the solid support in order to use a Merrifield synthesis to prepare leucine enkephalin. Include stereochemistry in your answer. Do NOT explicitly draw any hydrogen atoms in your structure or use abbreviations like OMe, COOH or Ph. (N terminus) Try-Gly-Gly-Phe-Leu (C terminus) НО. H₂N ✔ Edit Drawing H₂C CH₂ OH
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