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- Describe the ways in which each of the following pathogens can disarm their host’s immune system or manipulate it to their own advantage:a. Pathogenic strains of Staphylococcusb. Enveloped virusesIdentify which of the following immune responses is pivotal to the killing and elimination of helminths. a. killing by cytotoxic T cells in the lamina propria b. TH1-induced inflammation c. TH2-associated cytokines d. phagocytosis by intestinal macrophages e. systemic immune responses f. B-cell secretion of IgG.Which components are considered a barrier to pathogen entry? all that apply Select one or more: a. PRRs b. plasma cells c. mucus d. lymph nodes e. lysozyme
- In 2013, there was an outbreak of methicillin-resistant Staphylococcusaureus (MRSA) at an NFL training facility. One player suffereda career-ending infection to his foot and sued the team owners for $20 million for unsanitary conditions that contributed to the bacterialinfection. A settlement with undisclosed terms was reached in2017. MRSA is highly contagious and is spread by direct skin contactor by airborne transmission and can result in amputation or death.In addition, MRSA is very difficult to treat because it is resistant tomany antibiotics. For example, b -lactam antibiotics, such as penicillin,function by binding to and inactivating bacterial penicillin-bindingproteins (PBPs), which synthesize the bacterial cell wall. However,MRSA expresses an alternative type of PBP, called PBP2a encodedby the mecA gene. b -lactam antibiotics only weakly bind PBP2a,and thus cell wall synthesis can continue in their presence. Moreover,in a system somewhat analogous to the regulation of the…In 2013, there was an outbreak of methicillin-resistant Staphylococcusaureus (MRSA) at an NFL training facility. One player suffereda career-ending infection to his foot and sued the team owners for $20 million for unsanitary conditions that contributed to the bacterialinfection. A settlement with undisclosed terms was reached in2017. MRSA is highly contagious and is spread by direct skin contactor by airborne transmission and can result in amputation or death.In addition, MRSA is very difficult to treat because it is resistant tomany antibiotics. For example, b -lactam antibiotics, such as penicillin,function by binding to and inactivating bacterial penicillin-bindingproteins (PBPs), which synthesize the bacterial cell wall. However,MRSA expresses an alternative type of PBP, called PBP2a encodedby the mecA gene. b -lactam antibiotics only weakly bind PBP2a,and thus cell wall synthesis can continue in their presence. Moreover,in a system somewhat analogous to the regulation of the…In 2013, there was an outbreak of methicillin-resistant Staphylococcusaureus (MRSA) at an NFL training facility. One player suffereda career-ending infection to his foot and sued the team owners for $20 million for unsanitary conditions that contributed to the bacterialinfection. A settlement with undisclosed terms was reached in2017. MRSA is highly contagious and is spread by direct skin contactor by airborne transmission and can result in amputation or death.In addition, MRSA is very difficult to treat because it is resistant tomany antibiotics. For example, b -lactam antibiotics, such as penicillin,function by binding to and inactivating bacterial penicillin-bindingproteins (PBPs), which synthesize the bacterial cell wall. However,MRSA expresses an alternative type of PBP, called PBP2a encodedby the mecA gene. b -lactam antibiotics only weakly bind PBP2a,and thus cell wall synthesis can continue in their presence. Moreover,in a system somewhat analogous to the regulation of the…
- Which of the following is NOT a mechanism used by the immune system to fight multicellular parasites? Select one: a. Antibodies coating the pathogen surface bind to FcRs on mast cells, causing release of granule contents onto surface, and damage the parasite. b. Crosslinking of antibody binding to FceRI on eosinophils cells triggers release of granules, causing smooth muscle contractions. Muscle contractions in the mucosal tracts causes sneezing, coughing, vomiting or diarrhea, dislodging the parasite. d. The parasite is killed and broken down extracellularly, and then phagocytosed by macrophages. C.List three virulence factors and explain their role in establishing a disease. What is the difference between multidrug resistance and cross-resistance? What is the difference between MIC and MBC?Drug-resistant TB can be acquired via sequential mutations in the pathogen’s genome, or via transmission of a resistant pathogen from another person. How can these events be distinguished? Why is it important to know which is more prevalent?
- with HIV, explain the mechanism of intracellular infection and the role of reverse transcriptase. What would you explain about the process? What is the significance of the CD4+ count? ( Discuss the meaning of various ranges of CD4 counts.) List 5 opportunistic infections AND describe data to suggest whether or not a patient has such an infection.IgE IgA A Match the following diseases and disorders to the correct definition. A. Allergy/Hypersensitivity B. Autoimmune Disease B Day Tou in blood plasma and the chief antibody release during secondary responses 7. binds to the surface of mass cells and mediates an allergic response 8. predominant antibody found in mucus saliva and tears C. Immunodeficiency 1. AIDS & SCID 2. the immune system mounts an extraordinarily vigorous response to an otherwise harmless antigen 3. a hypersensitivity reaction 4. occurs when the production or activity of immune cells or complement is abnormal O 5. the body's own immune system produces the disorder; a breakdown of self tolerance 6. affected individuals unable to combat infections that would present no problems for normally healthy people 7. multiple sclerosis and rheumatic fever 8. a fever and contact dermatitis 9. Typical Symptoms of the acute response: tearing, runny nose, and itching skinThe World Health Organization (WHO, 2017) haslisted six steps individualscan take to prevent and control the spread of antibiotic resistance. a.One of the recommendations is “Never demand antibiotics if your health worker says you don’t need them.”Explain why when you have a flu, your health care worker would say that you do not need antibiotics. What are the other five recommendations?
